Tag: drug scheduling

  • NIDA Director Nora Volkow Talks Marijuana Research, Kratom

    NIDA Director Nora Volkow Talks Marijuana Research, Kratom

    Volkow testified before Congress about the difficulties of researching Schedule I drugs like marijuana.  

    Nora Volkow, director of the National Institute on Drug Abuse (NIDA), said during congressional testimony this week that designating a drug with Schedule I status can inhibit much-needed research. 

    “Indeed, the moment that a drug gets a Schedule I, which is done in order to protect the public so that they don’t get exposed to it, it makes research much harder,” Nora Volkow said, according to Marijuana Moment. “This is because [researchers] actually have to through a registration process that is actually lengthy and cumbersome.”

    Schedule I status is reserved for drugs that have no accepted medical use and are highly addictive. It includes heroin, but also marijuana. Other dangerous drugs, like cocaine and methamphetamine, are placed in the less restrictive Schedule 2 status.

    Many people would like to see marijuana reclassified, or unclassified all together. 

    Although marijuana is accepted for medical use in the majority of the country, it is “very difficult” for researchers to study the drug, because of its Schedule I status. Even in states where cannabis is legal for medical or recreational purposes, researchers and institutions can risk losing their federal funding if they study it without going through the federal process.

    This leaves many questions about the safety of products from marijuana to CBD, Volkow said. 

    The federal research process for marijuana includes lengthy delays because the Drug Enforcement Administration (DEA) limits the number of permits allowed for studying marijuana, and the amount of cannabis that can be grown for research purposes. Despite promising to issue more permits, the DEA has not yet significantly increased the ability of researchers to study marijuana

    Volkow also spoke about whether the herb kratom should receive Schedule I status. She said that doing so would “make it very difficult for our researchers to get ahold of the pharmacological compound itself.”

    Rep. Mark Pocan (D-WI) suggested that the benefits of scheduling kratom (like restricting public use) might be outweighed by the negative consequence of limiting research.

    “There seems to be—all the problems we’re trying to untangle right now around cannabis, marijuana specifically, because of Schedule I, I’d hate to see us put another drug there and then have to try to work backwards,” he said. “If we’re not there already, it allows you to continue to do the research.”

    NIDA, the DEA and the FDA are all working on a process to streamline drug research, looking for a “path that will allow researchers to work with Schedule I drugs in a safe way, but without actually expediting that process,” according to Volkow.

    View the original article at thefix.com

  • Marijuana Should Be Rescheduled, World Health Organization Says

    Marijuana Should Be Rescheduled, World Health Organization Says

    The UN authority is joining those who are demanding we take another look at marijuana’s classification.

    The World Health Organization (WHO) says that marijuana has been considered a Schedule IV drug, the Single Convention’s most restrictive category, for far too long. They believe marijuana’s current scheduling goes against science, but are making it clear they are stopping short of allowing legalization.

    The international scheduling of drugs was outlined in the Single Convention on Narcotic Drugs in 1961, which categorized drugs as most harmful and restricted for medical use in Schedule I to the more relaxed Schedule III.

    Their pattern is consistent with the United States’ scheduling order, up until Schedule IV. Breaking the pattern, the Single Convention defines Schedule IV drugs as an especially dangerous subset of Schedule I drugs requiring special attention and restrictions.

    Currently, marijuana is dual-categorized as Schedule I federally and a Schedule IV drug internationally, which places it on the same level as synthetic opioids.

    The WHO suggests that the marijuana plant and cannabis resins be taken off of Schedule IV, downgrading it to Schedule I internationally. They also want to explicitly state that CBD preparations with a THC content of lower than 0.2% will be considered as “not under international control” in any way.

    They also suggest that cannabis extracts, tinctures, and pharmaceutical THC compounds be taken from Schedule I down to Schedule III.

    Despite all the rescheduling, the WHO is not recommending that any country legalize marijuana, and in fact would consider such a move a violation of some stricter international treaties. However, the move is an admission that most governments have gotten marijuana wrong.

    “The placement of cannabis in the 1961 treaty, in the absence of scientific evidence, was a terrible injustice,” said legalization advocate Michael Krawitz. “Today the World Health Organization has gone a long way towards setting the record straight. It is time for us all to support the World Health Organization’s recommendations and ensure politics don’t trump science.”

    Despite not explicitly advocating for legalization, this may tip the scales in favor of countries that no longer want to enforce marijuana prohibition. Canada and Uruguay, which have decided to legalize marijuana even before the WHO’s announcement, are expected to support the move. More restrictive countries like China and Russia are expected to disapprove.

    The United States’ federal stance remains to be seen. Despite marijuana being legal in some form in more than half of the U.S., some say President Trump’s Attorney General nominee might go either way.

    View the original article at thefix.com

  • Feds Reschedule CBD Drugs But There's A Catch

    Feds Reschedule CBD Drugs But There's A Catch

    The rescheduling does not apply to all CBD drugs.

    Following the approval of CBD-based epilepsy drug Epidolex by the Food and Drug Administration (FDA), the US federal government has decided that, going forward, it will reschedule all CBD medications that the FDA approves.

    As of Friday, the rescheduling order has been published to the official register. While CBD medications becoming legalized is good news for advocates, the excitement was somewhat dampened by just how narrow the order is.

    “Specifically, this order places FDA-approved drugs that contain CBD derived from cannabis and no more than 0.1% tetrahydrocannabinols in schedule V,” reads the order.

    While this may not read like a big deal, the problem is that the FDA approval process is costly and lengthy, greatly limiting who can actually bring CBD products to market. So far, only Epidolex, made by GW Pharmaceuticals in the United Kingdom, has approval.

    “What this does not do is legalize or change the status of CBD oil products,” said a DEA spokesperson. “As of right now, any other CBD product other than Epidiolex remains a Schedule I controlled substance, so it’s still illegal under federal law.”

    The DEA takes this tough stance on CBD despite the fact that it carries many medicinal benefits while not providing any of the trademark “high” that marijuana does. Epidolex was deemed by the FDA to be safe enough to be used as treatment for debilitating epilepsy for children as young as or younger than one year old.

    Advocates argue that such strict criteria for CBD products means that any medicine, no matter how popular or effective, cannot qualify for FDA approval if it has any trace of THC.

    “We anticipated that Epidiolex will be the first of many potential FDA-approved medicines based on the cannabis plant. These are welcome alternatives,” said Paul Armentano, the Deputy Director of NORML. “But these products should not be regulated in such a manner that patients no longer have ready access to herbal cannabis — a product that humans have used safely and effectively as a medicine for thousands of years and is approved today by statute in 31 states.”

    View the original article at thefix.com