Tag: Kratom

  • Kratom withdrawal

    You know about Kratom addiction potential -you want to stop using Kratom!  So, what can you expect during Kratom withdrawal? And how can you cope? We explore here, and invite your questions about withdrawal from Kratom at the end.

    Severity of Kratom withdrawal

    From personal and anecdotal experience, the nature of withdrawal from Kratom and Kratom effects on body in terms of severity and occurrence seem to depend on a number of factors. The factors that contribute to Kratom withdrawal include:

    1. Duration of use – The length of time you have been taking Kratom. The longer you have been using it the more severe the symptoms.

    2. Type of Kratom – The type of Kratom you have been taking. Withdrawing from highly concentrated extracts of the alkaloids found in Kratom results in a worse withdrawal experience. Method of administration usually contributes to withdrawal symptoms, but as Kratom snort is not recommended, we assume that you are taking oral doses of Kratom.

    3. Previous mental health issues – Anecdotal evidence from online forums suggests that those who suffered from depression prior to becoming dependent on Kratom find withdrawals particularly difficult.

    4. Personal pain tolerance -It also seems that some people just manage Kratom withdrawals better. There are many who claim quitting Kratom even after more than a year’s daily use is no more difficult than quitting caffeine, while others talk about it like being hell on earth. So there certainly is a subjective element.

    My Experience withdrawing from Kratom

    I have personally withdrawn from Kratom after more than a year’s use and can therefore talk about my own withdrawals which I have been led to believe mirror those of others but not necessarily in their severity or duration.

    I took Kratom leaf twice a day, ever day for over a year. I decided one day to quit cold turkey; I used up the last of my supply and held my breath. I knew what was coming, I had tried to quit in the past but had always given up due to the crippling sadness that had enveloped me.

    Psychological Kratom Withdrawal

    Within 8 hours of my last dose of Kratom, I began to feel anxious and incredibly sad, despondent and plain depressed. It is difficult to describe the sense of loneliness and desolation I felt, everything seemed amazingly bleak. For me, this aspect of withdrawals was by far the most difficult to cope with and it continued for over a month. I must stress again that this was my experience others state that all their symptoms including the despondency disappeared after 4 or 5 days.

    Physical Kratom Withdrawal

    The other symptoms I experienced during Kratom withdrawal were all physical and ‘only’ lasted for 3 or 4 days. These self-reported symptoms during Kratom withdrawal are similar to those seen in individuals undergoing opiate withdrawal but are far less severe. If you have experienced other symptoms, please share them in the comments section of this article. The symptoms of physical withdrawal from Kratom included:

    • anxiety
    • cold-like symptoms
    • insomnia (the tick-tock of the clock just went on and on, night seemed as if it would never end)
    • lethargy/apathy
    • RLS – restless leg syndrome (it felt as if my legs were electrified and this contributed to insomnia)
    • sweating

    Coping with Kratom Withdrawals

    You can get through Kratom withdrawals. Kratom withdrawal can be a mere inconvenience for some and difficult for others. Here are some tips and suggestions based on my own experience about how you can cope during the period of Kratom withdrawal. Again, if you have other ideas, please leave them at the end.

    • I would advise anyone planning to withdraw from Kratom to seek the advice of a sympathetic physician. A prescription for a sedative like diazepam can help with the anxiety and insomnia. The problem is, though, that many doctors have never heard of Kratom and so will not know what to do.
    • You might want to take time off work/responsibilities during the initial stages of withdrawal as it can be very difficult to find the motivation to get tasks done.
    • It is also good to have a friend/loved one with you during the first few days as you can get quite despondent. This should be someone who knows that you are going through Kratom withdrawals and who knows what to expect as you go through the process of withdrawal.
    • If you are prone to depression anyway, then you really need to see a mental health care professional prior to quitting Kratom.

    Kratom withdrawal questions

    If you are going through Kratom withdrawal, you are not alone! We invite your questions about Kratom withdrawal. Or maybe you have an experience or feedback to share with other readers. Please let us know. We try to reply to all questions and comments with a personal and prompt response.

    View the original article at addictionblog.org

  • Kratom For Pain And Addiction Treatment: Is It Safe?

    Kratom For Pain And Addiction Treatment: Is It Safe?

    A new study explored the side effects and deaths linked to kratom.

    A recent study by a team at Binghamton University in New York found the drug kratom to be a threat to public health. The researchers looked at cases reported to the National Poison Data System—the data warehouse for the 55 poison control centers in the U.S.—and found 2,312 “kratom exposures” that led to toxicity.

    Of those, 935 cases involved just kratom, and negative symptoms reported included agitation, rapid heartbeat, vomiting, hallucinations, and coma.

    What Is Kratom?

    Kratom is a drug derived from the leaves of the Southeast Asian tree of the same name. The substance appears to interact with the opioid receptors in the brain, resulting in some pain relief properties similar to opioid drugs like heroin or OxyContin. It can also produce some stimulant and psychotropic effects.

    Kratom is still legal in the U.S. and has been increasingly marketed as a supplement that can relieve pain and even treat opioid addiction. 

    This marketing has led the U.S. Food and Drug Administration (FDA) to send official warnings to companies making these claims. Though it is legal, the FDA has not approved kratom for any treatment and considers the substance to be potentially dangerous.

    Toxicity Cases

    According to the Binghamton University study, four of the toxicity cases reported to the National Poison Data System resulted in deaths that were primarily caused by the kratom. This was potentially due to the fact that the drug acts like an opioid, the researchers say, therefore making it possible to experience dangerous overdose symptoms such as respiratory arrest.

    “Although it is not as strong as some other prescription opioids, kratom does still act as an opioid in the body,” said William Eggleston, clinical assistant professor of pharmacy practice at Binghamton. “In larger doses, it can cause slowed breathing and sedation, meaning that patients can develop the same toxicity they would if using another opioid product. It is also reported to cause seizures and liver toxicity.”

    Of the reported cases, 6.1% included seizures, 4.8% included hallucinations, 2.3% involved coma, and 0.6% involved cardiac or respiratory arrest. The study concluded that “kratom is not reasonably expected to be safe and poses a public health threat due to its availability as an herbal supplement.”

    Eggleston believes that kratom could be involved in treating opioid use disorder in the future, but his team concluded that more research is needed and it is not currently safe for use as an herbal supplement.

    View the original article at thefix.com

  • Kratom withdrawal

    Kratom withdrawal

    You know about Kratom addiction potential -you want to stop using Kratom!  So, what can you expect during Kratom withdrawal? And how can you cope? We explore here, and invite your questions about withdrawal from Kratom at the end.

    Severity of Kratom withdrawal

    From personal and anecdotal experience, the nature of withdrawal from Kratom and Kratom effects on body in terms of severity and occurrence seem to depend on a number of factors. The factors that contribute to Kratom withdrawal include:

    1. Duration of use – The length of time you have been taking Kratom. The longer you have been using it the more severe the symptoms.

    2. Type of Kratom – The type of Kratom you have been taking. Withdrawing from highly concentrated extracts of the alkaloids found in Kratom results in a worse withdrawal experience. Method of administration usually contributes to withdrawal symptoms, but as Kratom snort is not recommended, we assume that you are taking oral doses of Kratom.

    3. Previous mental health issues – Anecdotal evidence from online forums suggests that those who suffered from depression prior to becoming dependent on Kratom find withdrawals particularly difficult.

    4. Personal pain tolerance -It also seems that some people just manage Kratom withdrawals better. There are many who claim quitting Kratom even after more than a year’s daily use is no more difficult than quitting caffeine, while others talk about it like being hell on earth. So there certainly is a subjective element.

    My Experience withdrawing from Kratom

    I have personally withdrawn from Kratom after more than a year’s use and can therefore talk about my own withdrawals which I have been led to believe mirror those of others but not necessarily in their severity or duration.

    I took Kratom leaf twice a day, ever day for over a year. I decided one day to quit cold turkey; I used up the last of my supply and held my breath. I knew what was coming, I had tried to quit in the past but had always given up due to the crippling sadness that had enveloped me.

    Psychological Kratom Withdrawal

    Within 8 hours of my last dose of Kratom, I began to feel anxious and incredibly sad, despondent and plain depressed. It is difficult to describe the sense of loneliness and desolation I felt, everything seemed amazingly bleak. For me, this aspect of withdrawals was by far the most difficult to cope with and it continued for over a month. I must stress again that this was my experience others state that all their symptoms including the despondency disappeared after 4 or 5 days.

    Physical Kratom Withdrawal

    The other symptoms I experienced during Kratom withdrawal were all physical and ‘only’ lasted for 3 or 4 days. These self-reported symptoms during Kratom withdrawal are similar to those seen in individuals undergoing opiate withdrawal but are far less severe. If you have experienced other symptoms, please share them in the comments section of this article. The symptoms of physical withdrawal from Kratom included:

    • anxiety
    • cold-like symptoms
    • insomnia (the tick-tock of the clock just went on and on, night seemed as if it would never end)
    • lethargy/apathy
    • RLS – restless leg syndrome (it felt as if my legs were electrified and this contributed to insomnia)
    • sweating

    Coping with Kratom Withdrawals

    You can get through Kratom withdrawals. Kratom withdrawal can be a mere inconvenience for some and difficult for others. Here are some tips and suggestions based on my own experience about how you can cope during the period of Kratom withdrawal. Again, if you have other ideas, please leave them at the end.

    • I would advise anyone planning to withdraw from Kratom to seek the advice of a sympathetic physician. A prescription for a sedative like diazepam can help with the anxiety and insomnia. The problem is, though, that many doctors have never heard of Kratom and so will not know what to do.
    • You might want to take time off work/responsibilities during the initial stages of withdrawal as it can be very difficult to find the motivation to get tasks done.
    • It is also good to have a friend/loved one with you during the first few days as you can get quite despondent. This should be someone who knows that you are going through Kratom withdrawals and who knows what to expect as you go through the process of withdrawal.
    • If you are prone to depression anyway, then you really need to see a mental health care professional prior to quitting Kratom.

    Kratom withdrawal questions

    If you are going through Kratom withdrawal, you are not alone! We invite your questions about Kratom withdrawal. Or maybe you have an experience or feedback to share with other readers. Please let us know. We try to reply to all questions and comments with a personal and prompt response.

    View the original article at addictionblog.org

  • Kratom-Related Deaths Analyzed By The CDC

    Kratom-Related Deaths Analyzed By The CDC

    The herbal supplement has been targeted as a “drug of concern” by the FDA and DEA.

    The number of deaths associated with kratom appears to be rising.

    A new report by the CDC analyzed data from 27 states on 27,338 overdose deaths between July 2016 and December 2017. A small number was attributed to kratom.

    “Kratom was determined to be a cause of death (i.e., kratom-involved) by a medical examiner or coroner for 91 of the 152 kratom-positive decedents, including seven for whom kratom was the only substance to test positive on postmortem toxicology, although the presence of additional substances cannot be ruled out,” the report read.

    The herbal supplement credited with helping recovery from substance use disorder has been targeted as a “drug of concern” by the Food and Drug Administration (FDA) and Drug Enforcement Administration (DEA).

    Some people in recovery say the plant, native to Southeast Asia, was vital to their recovery from drugs and alcohol, chronic pain, post-traumatic stress disorder (PTSD) and more. But with every success story, there is a person struggling to quit kratom as well.

    A majority of the kratom-involved deaths involved people with a history of substance use disorder. A significant majority of the kratom-positive decedents were Caucasian.

    The data also showed that “multiple substances [were] detected for almost all decedents.” The most common were fentanyl and fentanyl analogs, then heroin, benzodiazepines and prescription opioids.

    The FDA has railed hard against kratom, stating last year that “compounds in kratom make it so it isn’t just a plant—it’s an opioid.”

    The February 2018 statement cited 44 deaths associated with kratom use. Prior to that, in a November 2017 advisory, the FDA reported 36 deaths related to kratom.

    The FDA said it is “especially concerned” about people who use kratom to treat opioid withdrawal, and though it states that it is open to reviewing evidence that kratom does have healing properties, it so far has not come across any “that would meet the agency’s standard for approval,” and warns against using kratom to treat medical conditions or as an alternative to prescription opioids.

    “While kratom may have useful effects, right now, it’s wholly unregulated,” Henry Spiller, director of the Central Ohio Poison Center, told ABC News.

    Only a few U.S. states have outright banned the plant. Some states are considering legislation to regulate the plant, rather than prohibiting it.

    View the original article at thefix.com

  • Kratom-Related Calls To Poison Centers Skyrocket

    Kratom-Related Calls To Poison Centers Skyrocket

    The majority of the calls to poison centers about kratom were made by men over the age of 20. 

    As the debate continues to swirl over the potential health benefits as well as hazards of kratom use, researchers have found that calls to poison control centers in regard to the use of the herbal supplement have increased more than 50-fold in recent years.

    Their findings show that kratom-related calls to poison control centers across the country rose from 13 in 2011 to 682 in 2017. Nearly 10% of those calls involved an individual who experienced life-threatening side effects, and 11 individuals who made calls later died—though the majority of these were reported to have taken another substance in addition to kratom.

    The researchers concluded their report by requesting enhanced information about kratom and increased regulation by the Food and Drug Administration (FDA) on kratom products.  

    The study, published in the journal Clinical Toxicology, sought to determine the number of calls to poison control centers that involved kratom, as well as demographic information of the callers. To find that information, researchers reviewed data on 1,800 calls from the National Poison Data System.

    Though 2011 was designated as the beginning of the study period, 65% of the calls were received in 2016 and 2017, or the final two years of the study.

    As Live Science noted, the majority of the cases (71%) involved men over the age of 20. Approximately 2.5% of the cases involved children under the age of 12 who were exposed to kratom, including seven newborns; five of that group reportedly experienced symptoms of withdrawal due to exposure in the womb, while another newborn received kratom through breastfeeding.

    Approximately one-third of the cases required treatment at a health care facility, and as mentioned, nearly 10% reported life-threatening or disabling effects. The most commonly reported side effects were agitation, elevated heart rate and/or blood pressure, nausea and/or vomiting, and drowsiness or lethargy.

    Those who took kratom with another drug were more than twice as likely to experience a more serious response than those who consumed kratom alone; of the 11 reported fatalities, nine were reported to have ingested other substances including alcohol, fentanyl, cocaine and benzodiazepines.

    Kratom use has increased in recent years due to the widespread belief in its healing properties. According to the American Kratom Association, between 3 and 5 million people in the United States use it for various reasons.

    Herbal supplements made from the plant, which can be found in Southeast Asia, have been used to treat chronic pain, depression and dependency on opioids or alcohol.

    Proponents of kratom have found their support opposed by the FDA, which has not approved kratom for any medical use, and by the Department of Health and Human Services and Drug Enforcement Administration, which briefly attempted to ban the substance, though that pursuit was shut down by public outcry. 

    The researchers offered a number of recommendations for future action regarding kratom. They advised the medical community to disseminate more information about the risks of kratom, especially for women during pregnancy and breastfeeding.

    They also advised the FDA to increase regulation of kratom products.

    “At a minimum, they should be free of potentially harmful ingredients, provide a uniform strength of active ingredients and have appropriate labeling,” the researchers wrote in their study’s conclusion.

    View the original article at thefix.com

  • Thailand To Review Medical Marijuana, Kratom Legalization Proposal

    Thailand To Review Medical Marijuana, Kratom Legalization Proposal

    The kratom/marijuana legalization bill has received substantial support from the National Legislative Assembly and the Thai public. 

    Lawmakers in Thailand have unanimously accepted an initiative to review a bill that would legalize the production, import and export of marijuana and the herbal supplement kratom for medical use.

    The amendment, proposed by members of the National Legislative Assembly (NLA), would revise the country’s Narcotics Act and allow patients to access medical marijuana and kratom for therapy and grant access to the Red Cross and medical professionals. The initiative must go before another panel of lawmakers for review, but support for legalization has already netted widespread approval among the Thai population, according to the NLA’s digital forum.

    The amendment bill, proposed by 44 members of the NLA, provides guidelines for medical use of marijuana and kratom, which under the current Narcotics Acts are listed as Category V drugs and illegal to consume, possess, produce, distribute, import and export, with imprisonment and/or substantial financial penalties levied against those convicted of such charges.

    As High Times noted, marijuana and kratom would be made available to approved patients as treatment and could be obtained from the Government Pharmaceutical Organization, the Red Cross, local administrative agencies, and medical professionals and ministries. Individuals who have a record of previous narcotics-related charges may not partake in the program, according to the Bangkok Post. Production sites and grow programs would be overseen by Thailand’s public health minister and the Office of the Narcotics Board.

    The amendment bill has to date received substantial support from the NLA and the Thai public. An initial read received 145 votes of support from NLA members while a public hearing on the NLA’s digital platform saw 99.03% of participants approve the bill’s provisions. Health care professionals and legal academics have also lobbied in support of revising the Narcotics Act in favor of providing Thai citizens with the alleged medical benefits of both substances.

    “The Narcotics Act was drafted and first enforced in 1985, so we can see it’s not only out of date, but also restricts people’s rights too much, especially considering the enormous benefits in healthcare that could come from medical cannabis and kratom,” said Paisal Limstit of Thammasat University’s Faculty of Law.  

    The NLA must now establish a 29-member panel to review the bill; the process, according to the Bangkok Post, takes approximately 60 days.

    Should the bill pass into law, the Thai government will face an uphill battle with the marijuana that is currently available in the country. Laboratory tests on marijuana seized by police revealed the presence of pesticides and heavy metals, which the Department of Medical Sciences determined was not suitable for consumption, medical or otherwise.

    View the original article at thefix.com

  • FDA Tries To Blame Kratom In Newborn Withdrawal Case

    FDA Tries To Blame Kratom In Newborn Withdrawal Case

    The agency claims it is aware of four other NAS cases involving infants exposed to kratom in utero.

    A new case report published in the journal Pediatrics suggests that kratom was the cause of a newborn’s withdrawal symptoms. While the Food and Drug Administration (FDA) and other naysayers of the herbal supplement say this is a prime example of kratom’s potential for abuse and addiction, researchers say there’s not enough information to draw any hard conclusions.

    According to the case report, a former oxycodone user gave birth to a boy who showed signs of drug withdrawal—he was jittery, screaming, and required a morphine treatment to stay alive.

    The mother reported that she had used oxycodone for almost a decade. But she completed a treatment program and was off the drugs during her pregnancy. Indeed, no opioids were detected in a drug test.

    According to the woman’s husband, she had kratom tea every day to treat her withdrawal symptoms and help her sleep. Kratom, a plant that is native to Southeast Asia, has a fierce and loyal following of people who say it has helped them manage pain and treat opioid withdrawal.

    But people should practice caution, says lead author of the case report Dr. Whitney Eldridge, a neonatologist at BayCare Health System in Florida. “I fear that women making genuine commitments to overcome their dependency may develop a false sense of safety by using a substance that is advertised as a non-opioid alternative,” she said.

    As CNN notes, there is no explicit link between kratom and neonatal abstinence syndrome (NAS) made in the case report.

    There is not enough information to do so, says Dr. Andrew Kruegel, associate research scientist at Columbia University. “The main limitation is that we don’t know anything about the dosage that the mother was taking. Without that information, you can’t really extrapolate too much.” Nor was it verified—other than from the husband’s account—that the substance the mother was ingesting was indeed kratom.

    According to the FDA, the boy’s case “further illustrates the concerns the FDA has identified about kratom, including the potential for abuse and addiction.”

    The agency claims it is aware of four other NAS cases involving infants exposed to kratom in utero.

    In April, FDA Commissioner Scott Gottlieb went so far as to state that “compounds in kratom make it so it isn’t just a plant—it’s an opioid.”

    View the original article at thefix.com

  • How to Taper Off Suboxone: A Survival Guide

    How to Taper Off Suboxone: A Survival Guide

    “Fear is common and normal for a number of reasons, but the fear usually gives way to a sense of confidence and optimism when a taper is done correctly…Be patient.”

    Note: This article is not intended as a replacement for medical advice. This is merely the experience of 21 people interviewed by the author who have successfully tapered off buprenorphine-based medications (Suboxone, Zubsolv, Bunavail, Subutex, etc.) or significantly reduced their dose. Please consult your doctor before beginning a taper. 

    After two and a half years of taking Suboxone, I’ve decided that it’s time to start the tapering process. I don’t like having to rely on this little orange film strip each morning to get out of bed, the tidal wave of nausea, being constantly hot, the restless legs, and the constipation. This is an incredibly difficult decision because Suboxone has saved my life. Additionally, studies have demonstrated the effectiveness of Suboxone and found it’s reduced overdose death rates by 40 percent. 

    Some people decide that it is best for them to take Suboxone for life. Shannon has been taking 16 milligrams of Suboxone for 17 years and has no intention of tapering. She said: “I’m never getting off, why fix something that isn’t broken? I love life now. I’m a great mother, wife, daughter, sister, aunt, and trustworthy friend to all those that know and love me. I have absolutely no shame being a lifer. I’ve been to the depths of hell and now I’m in heaven. I believe without subs, I would be dead.”

    Like Shannon, fear of relapse and withdrawals makes me terrified of coming off Suboxone. I imagine waking up panicked and glazed in sweat, running to the bathroom to puke and worst of all, the black hole of depression and existential dread that is common with opioid withdrawal. These are common fears for people coming off opioid addiction treatment medications. In order to help others like me who are interested in tapering, I researched this topic and surveyed 21 people: 13 have successfully tapered off Suboxone and eight have significantly lowered their doses and are currently at or under six milligrams per day.

    Slow Taper

    Sixteen of 21 people I surveyed reported using a slow taper to come off or lower their dose. Dr. Jeffrey Junig of the Suboxone Talk Zone Blog suggests that the optimal dose to “jump” or quit taking Suboxone is .3 mg (about 1/3 of 1 mg).

    Junig writes: “I have had many patients taper successfully off buprenorphine. Fear is common and normal for a number of reasons, but the fear usually gives way to a sense of confidence and optimism when a taper is done correctly…Be patient. Tapering by too much, or too quickly, causes withdrawal symptoms that lead to ‘yo-yos’ in dose.”

    Amanda* agrees with Junig’s advice not to try to jump from too high of a dose. She said that when she jumped from 2 mg cold turkey it was “40 days of hell.”

    To avoid a hellish experience like Amanda’s, Junig advises reducing your dose by 5% or less every two weeks or 10% every month. Sound confusing? Junig simplifies: Use scissors to cut half of an 8 mg film. Then cut half of that, then half again. Put the doses in a pill organizer so they don’t get lost or accidentally consumed by children or pets.

    Holistic Remedies

    There are a handful of holistic remedies that can help with the tapering process. Folks I surveyed said that yoga, meditation, and healthy eating are pillars of their recovery. Studies have confirmed the benefit of yoga for improving quality of life in those withdrawing from opioids as it alleviates anxiety, restless legs, insomnia, and even nausea.

    Sarah said: “I tapered with a clean diet with digestible nutrient-dense food and smoothies and stayed hydrated. I got plenty of sun, used yoga and exercise too.”

    Others recommended vitamins and other supplements including: L-Tyrosine, DLPA, Vitamin C, Omega 3 Fish Oil, and ashwagandha. They used melatonin for sleep and Kava tea for relaxation. (Consult your physician before taking any supplements. Even benign substances may interact with other medications or have unintended side effects.)

    Marijuana

    Four out of 21 people polled used marijuana to deal with the difficult side effects of tapering off Suboxone. Barry said: “I know that some people may not see marijuana as a way that should be used to taper, but for me I was desperate to try anything that worked. I consider marijuana a lesser of evils. It helped with restless legs, nausea, pain, and anxiety.”

    Marijuana may now be a viable option for those who wish to try it, because it’s now legal for medical use in 29 states and for recreational use in nine states plus Washington DC. Unlike opioids, marijuana provides pain relief with a lower risk of addiction and nearly no risk of overdose. Plus, comprehensive studies like this one from the American Pain Society found that medical cannabis use is associated with a 64 percent decrease in opiate medication use.

    While studies have supported the use of marijuana to reduce opioid use, further research needs to be done as reported in the The Daily Beast. Dr. Junig also advises that patients should not start new mood-altering, addictive substances in order to taper off Suboxone.

    CBD Oil

    Three of the Suboxone patients polled were able to taper with the help of cannabidiol, also known as CBD oil. Experts emphasize the distinction between marijuana and CBD oil: CBD oil is not psychoactive, meaning that it doesn’t make patients feel “high” like the THC in marijuana. CBD oil may be a more viable option for people in states where marijuana has not been legalized and also for those who do not want mood altering affects, but strictly relief from physical symptoms. “I used CBD oil during the taper because pot isn’t legal in my state and it helped with restless legs, sleep, and anxiety,” Pablo said.

    A 2015 study in Neurotherapeutics examined the therapeutic benefits of cannabidiol as a treatment for opioid addiction. They found that CBD oil is effective in reducing the addictive properties of opioids, mitigating withdrawals, and lessening heroin-related cravings. Specifically, it relieved physical symptoms such as: nausea, vomiting, diarrhea, runny nose, sweating, cramping, muscle spasm. Additionally, it treats mental symptoms like anxiety, agitation, insomnia, and restlessness. The study states CBD oil is effective with minimal side effects and toxicity.

    Kratom

    In our survey, the people who tried kratom claim that the herb is a controversial yet effective way for tapering from Suboxone. Some experts agree. According to the Mayo Clinic: “In Asia, people have used kratom in small amounts to reduce fatigue or treat opium addiction. In other parts of the world, people take kratom to ease withdrawal, feel more energetic, relieve pain, or reduce anxiety or depression.”

    Four of the individuals surveyed used kratom for tapering off Suboxone. Christine said, “I was very tired when coming off Suboxone, so kratom helped give me the energy to work, clean my house, and take care of my kids.”

    Cristopher R. McCurdy, PhD, a professor of medicinal chemistry at University of Florida’s College of Pharmacy in Gainesville, studies kratom. McCurdy told WebMD: “I definitely believe there is legitimacy to using kratom to self-treat an opiate addiction.”

    Despite these positive reviews, the Mayo Clinic and Web MD caution that kratom can also lead to addiction and withdrawal. According to an article on WebMD, “There’s little research on the herb’s effects on people, and some experts say it also can be addictive. The herb is illegal in six states and the District of Columbia, and the Drug Enforcement Administration is considering labeling it as a Schedule I drug…For now, the agency calls it a ‘drug of concern.’”

    Pharmaceutical Remedies

    Five of the people surveyed said that they tapered with the support of medications prescribed by their doctors to treat individual withdrawal symptoms. It is best that patients talk with their doctors and addiction professionals to see if a particular medication is right for their situation.

    Happy tapering! I plan on writing more in the future about my experience and progress tapering off Suboxone. If you’re embarking on this journey, I wish you luck!

    The names of some individuals have been changed to respect their privacy.

    Have you successfully tapered off Suboxone or methadone? Or are you a “lifer” like Shannon? We’d love to hear your thoughts, experiences, and tips in the comment section.

    View the original article at thefix.com

  • Anatomy of a Relapse

    Anatomy of a Relapse

    When my father died, I hadn’t been to a meeting in over a year. I had no active knowledge of how to apply healthy coping mechanisms to a devastating situation so I just went back to what I knew: opioids and numbness.

    Two years ago I wrote a controversial feature for The Fix, “I Take Psychedelic Drugs and I’m in Recovery.” It was controversial in the sense that the response from the publication’s readers — many of whom have an obviously vested interest in topics related to addiction recovery — ranged from sarcastic, hyperbolic criticism to open-minded consideration, with some even condoning the perspective I was sharing.

    The reason I chose to write this honest, albeit uncomfortable “Part 2” of sorts, is to do what folks in certain recovery circles do best (when at their best): share experience, strength, and hope, so that whoever may be listening, reading, or watching may, at the very least, relate and ideally, be helped by it.

    Full disclosure: My name is not James Renato. It’s a pseudonym, adopted out of respect for the principle of anonymity in a 12-step offshoot group I am a member of. It’s also, of course, meant to protect myself from facing unnecessary personal backlash merely for engaging in public discourse.

    Now that I’ve successfully buried the lede, in the spirit of qualifying in the style of an Alcoholics Anonymous meeting: “here’s what it was like, what happened, and what it’s like now.”

    Last April, I ended a full-blown relapse of what previously was an opioid use disorder in remission. In other words, I’d started injecting heroin again eight months earlier, for the first time in over six years.

    It was the culmination of a tripartite experiment involving: firstly, a noble attempt to actively practice a program I helped form (namely, Psychedelics in Recovery [PIR]). Secondly, a misguided lack of acknowledgement that I was inviting a serious risk to my life by no longer practicing abstinence (not just from psychedelics). And lastly, a gradual ceasing of the daily commitment to personal growth in the form of meeting attendance, regular contact with a sponsor, associating with peers in recovery, and just continuing to work on improving the overall quality of my life and relationships with others.

    People in recovery continue to regularly engage in their program of choice because life is unpredictable, and the myriad tools we learn are not always the same ones we rely on for every situation. One day a simple phone call can be all that’s necessary to get ourselves out of “a funk.” Another day it’s hitting four meetings, extensively praying and meditating, and taking a newcomer out for coffee because we were just laid off from a full-time job and needed to avoid the danger that can come from “feeding the poor me’s.”

    In my case, when I stopped participating in my ongoing recovery process, I made an inexplicably impulsive decision to reintroduce opioids to my system. When the DEA announced that they were planning to classify kratom as Schedule 1, I purchased a kilogram from an online vendor for literally no good reason. Several weeks after I received the package of high potency kratom leaf powder (of the “super green vein” variety), I conducted a dose-response self-experiment. I have a history of progressing down the road of “continued use [of opioids] despite negative consequences” (the current best definition of addiction), and within a few months I developed a dependency and went through the entire kilo, despite attempts to reassure my partner that the amount I purchased was intended to last for years, and would only be used when absolutely necessary.

    Right around the time my supply ran out, a friend who had no idea of the habitual relationship I had with kratom use told me about another mild opioid sold on the supplement market called tianeptine sulfate. Tianeptine had undergone clinical trials as an opioid-based antidepressant in the 1990s but did not progress past the second of three phases required by the Food and Drug Administration (for unknown reasons). With the drug’s unscheduled status, enterprising entrepreneurs in the unregulated supplement industry capitalized on tianeptine’s acute, short-acting antidepressive effects at low doses, but savvy opioid connoisseurs discovered the euphoric high it brought on (also short-acting) at much larger doses.

    My kratom habit switched to tianeptine, in large part because of how disgusting I found the taste of the tea I made from brewing the leaf powder, and the hassle of masking the taste by encapsulating the amount I needed to take to reach the effects I preferred. In addition to the perfect storm of things perpetuating my now very active addiction, I’d even stopped attending PIR meetings, was becoming increasingly disillusioned with my graduate studies, and was now too ashamed to admit to anyone that I was seriously struggling.

    Then, tragedy struck. My father, a seemingly healthy 64-year-old on the verge of retirement, suffered a sudden, fatal heart attack on a scuba diving trip in the Caribbean. I was already treading on thin ice, and this kind of event is something I’d long heard people in 12-step meetings share reservations over in their commitment to recovery. But I hadn’t been to a meeting in over a year at this point, so I had no active knowledge of how to apply healthy coping mechanisms to a devastating situation. It was a situation that countless people have gone through, relying on their recovery program to help them navigate as safely as possible, but I’d learned from the opioids I’d been relying on that if I could just figure out how to stay numb 24/7, that’s all I needed to do.

    After the standard bereavement rituals of a wake, funeral, and burial at the family cemetery plot, which was actually a very supportive and comforting assemblage of close friends, loved ones, and long-lost acquaintances paying their respects, I ended up alone in a dangerous situation. I called my old dealer, whose number I still had memorized after over six years of no contact, and one night drove out to meet him just like old times. No need to bother snorting or smoking whatever powder he claimed to be heroin; I had already been well reacquainted with the too-mild results of those routes of administration, so I went right back to the needle.

    I’ll spare you all the details of the familiar downward spiral and just hit on the highlights: I depleted all of my savings, misappropriated funds from an award I’d received, stole thousands of dollars from my father’s still active bank account, then my mother’s shared account, totaled my partner’s car from multiple accidents, couldn’t maintain my job, took a leave of absence from school, and wreaked a devastating emotional toll by shattering the trust of my friends and family.

    Miraculously, I was not arrested, did not overdose (though I came close), and was not robbed (although certainly ripped off repeatedly). About six weeks before I was confronted about the missing money, I obtained a 15-day supply of Suboxone from a chemical dependency clinic, but I shelved it, having no intention of taking it. Towards the end of the first week of April, my partner was preparing to go out of town for the weekend, and I had just been asked by my mom if I knew anything about the empty bank accounts.

    I woke up alone on April 5th, a Thursday, and began my morning ritual of taking stock of the heroin I had left, trying to negotiate with myself on how to titrate the remaining amount throughout the day. I always lost these negotiations and usually just did all of it, or the rest soon thereafter. But after I injected the last of it, I didn’t feel the slightest bit high. Instead, I wept. With only the company of my two cats (who avoided me as much as possible), I realized that I could no longer hide. I faced a crossroads: I could escalate my lies and attempt to find another hustle — knowing full well how inept I am when it comes to actual criminal behavior — or, surrender.

    I remembered the Suboxone sublingual film, and without really taking any time to talk myself out of it, I tore open the package and put the film under my tongue — realizing that if I kept it in long enough to absorb the full dose, I’d be inducing opioid withdrawal. I felt incredibly lonely and remorseful, so I begged my partner to come home from work, admitting to her what she had long known but felt powerless to help me with. Then I texted my mom, hinting to her that I was in a desperate state, and needed to spend the weekend at her home or I wouldn’t be able to “see things through.”

    Tears were pouring down my face in these moments, and I was wailing — one of the deepest emotional pits of despair I’ve ever found myself in. I’ve never found the concept of rock bottom useful. Instead of labeling that moment or attempting to explain it, I attribute my actions to grace.

    A New Perspective on an Old Idea

    I’m a wholehearted believer in the potential of psychedelics or plant medicines in recovery. I have heard first-hand tremendously powerful stories from people who have overcome their reluctance and the doubt instilled upon them by their peers, and are actively integrating the spiritual insights from their psychedelic journeys into their lives. PIR continues to meet regularly via an online meeting, twice a month, and our members gather from across whatever time zones they’re in to come together and share experience, strength, and hope with each other. We’ve formulated a list of guiding principles, meant to clarify the scope of our suggested program. I had strayed from those principles and met the predictable outcome we’re hoping to help others avoid.

    There are ongoing FDA-approved clinical trials for the use of psilocybin (the active pro-drug of psilocin, a psychedelic found in several species of mushrooms) for nicotine, cocaine, and alcohol use disorder, as well as a recently approved study in Europe looking at MDMA-assisted psychotherapy for treatment of alcohol use disorder. While these trials are aimed at treatment of an acutely manifesting substance use disorder, one of the primary guidelines for PIR is that our members should have a firmly established foundation of recovery in a primary qualifying recovery fellowship, and are actively working that program as it’s suggested.

    Recently, now just five months out from ending my relapse, I considered having a ceremony with iboga (the alkaloid-containing root bark of a shrub indigenous to western equatorial Africa), as I wanted to commemorate the one-year anniversary of my father’s death. After soliciting the feedback of my support network, none of whom gave me any advice, but instead offered honest and open perspective to help guide me in making a decision, I decided against it. Ultimately, the decision to commemorate the anniversary unaided came during several of my morning sitting meditations, a practice that has become vital to my ongoing recovery.

    Instead, friends, family, and loved ones gathered at our house on the anniversary day, and shared memories, pictures, and videos of my father.

    View the original article at thefix.com

  • Kratom Draws Support And Controversy As Opioid Addiction Treatment

    Kratom Draws Support And Controversy As Opioid Addiction Treatment

    “It’s like a cruel joke that I finally found something that works and the FDA and DEA want it banned,” said one kratom user. 

    A controversial supplement, kratom, could have benefits when it comes to treating opioid use disorder, according to a new study. However, there is still much controversy around it due to safety concerns.

    Kratom is a psychoactive drug that comes from the leaves of Mitragyna speciosa, which is an Asian plant in the coffee family

    Some believe it is effective for treating substance use disorders, but organizations such as the Food and Drug Administration (FDA) and the Drug Enforcement Administration are wary of that. In fact, the DEA even attempted to ban the substance.

    In February, FDA commissioner Scott Gottlieb spoke against kratom, saying “there is no evidence to indicate that kratom is safe or effective for any medical use.”

    Scott Hemby, a professor of pharmaceutical science at High Point University in North Carolina, led a new study recently published in Addiction Biology, which found that kratom may in fact have some benefits.

    Kratom has two main ingredients: mitragynine (MG) and 7‐hydroxymitragynine (7‐HMG). MG accounts for 60% of the compound in the plant while HMG is about 2%. Using rats, Hemby’s study examined how both these ingredients affect the brain. 

    Hemby and other researchers allowed rats to self-administer both components of kratom. They found that the rats quickly began self-administering HMG, but did not have interest in MG.

    “In other words, while one of kratom’s main compounds appeared to be addictive, the other wasn’t at all—in fact, it appeared to have the opposite effect,” Business Insider reported

    Because kratom affects some of the same receptors in the brain as opioids, the FDA announced in February that it would be called an “opioid.” But others believe kratom could be beneficial and treat cravings while reducing symptoms of withdrawal and the likelihood of relapse.

    The results of the study suggest that it could be beneficial to breed the plant to have higher concentrations of one compound versus the other. However, the results are preliminary because the study was not done on humans.

    Some people, such as 26-year-old Bryce Avey, began using kratom because they could not get access to other opioid treatments like buprenorphine and naltrexone. “It’s like a cruel joke that I finally found something that works and the FDA and DEA want it banned,” Avey told Business Insider

    David Juurlink, professor of medicine at the University of Toronto, told Business Insider that the use of kratom makes sense, as it affects the same brain receptors as opioids. “It makes sense that this product would mitigate the symptoms of opioid withdrawal or allow someone to transition from a higher dose to lower dose, or help get them off of opioids altogether,” he said.

    Business Insider notes that concern about the supplement arises because there is no “quality oversight of kratom,” meaning people don’t know what the pills actually contain.

    “Personally, I would never take this stuff,” Juurlink told Business Insider. “When you go to a pharmacy, you know there’s quality control, you know precisely how much you’re getting, and you know exactly what you’re getting. With this, it’s impossible to know.”

    View the original article at thefix.com