Tag: marijuana and fertility

  • Does Marijuana Affect Sperm Count?

    Does Marijuana Affect Sperm Count?

    A new study suggests it does—but not in the way you might think. 

    Harvard researchers were surprised to find that men who have smoked marijuana had better sperm counts than their counterparts who had never used cannabis—but scientists are cautioning that the link does not mean there is a causal connection between smoking marijuana and increased fertility. 

    A study published this week in the journal Human Reproduction found that men who had smoked marijuana at some point in their lives had higher sperm counts, which is associated with increased fertility.

    Researchers examined 1,143 semen samples from 662 men, all of whom were undergoing fertility treatments with their partners at the Massachusetts General Hospital Fertility Center.

    “Men who had ever smoked marijuana had significantly higher sperm concentration than men who had never smoked marijuana,” study authors wrote. There was no difference in sperm count between current and previous marijuana smokers. 

    These findings came as a surprise, since previous research has indicted that smoking marijuana had a negative effect on fertility. A 2015 study found that men who smoked weekly had a lower sperm count than those that did not, and a study published in 2018 found that THC can change the structure of sperm.  

    Researchers said that it’s possible that low-level exposure to cannabis could aid fertility by stimulating the endocannabinoid system in the brain. However, they said that it’s just as likely that testosterone levels affect both the likelihood that a man uses cannabis (a risk-taking behavior) and his sperm production. 

    “Our findings could reflect the fact that men with higher testosterone levels are more likely to engage in risk-seeking behaviors, including smoking marijuana,” Dr Feiby Nassan, who was involved with the research, told Bloomberg

    Allan Pacey, professor of Andrology at the University of Sheffield in Britain, said that men who are trying to have a child should continue to avoid cannabis. 

    “As the authors point out, men with higher sperm concentrations are likely to have more testosterone in their bodies and thus may be more likely to smoke marijuana because simply they are willing to take more risks,” he said. “In conclusion, I am not convinced that this paper moves us any further forward in this debate. Moreover, nor does it give support to any apparent fertility benefits of smoking marijuana. In my opinion, this should be avoided at all costs in any couples trying to start a family.” 

    Lead author Dr. Jorge Chavarro said that the findings highlight the need for more research into the effects of cannabis on male fertility. 

    “These unexpected findings highlight how little we know about the reproductive health effects of marijuana, and in fact of the health effects of marijuana in general,” he said. “Our results need to be interpreted with caution and they highlight the need to further study the health effects of marijuana use.”

    View the original article at thefix.com

  • Does Pot Use Really Affect Sperm Count?

    Does Pot Use Really Affect Sperm Count?

    A Duke University study explored the possible correlation between THC concentrations in urine and viable sperm count.

    The research on whether marijuana can have a detrimental effect on sperm production in men has produced varying results, with some studies suggesting that usage may result in a lower sperm count and/or abnormal sperm genetics, while others claim no correlation exists.

    New research from Duke University Medical Center supports the former position by showing that high concentrations of THC – the compound in marijuana that produces a euphoric response – in urine appeared to correspond to a lower sperm count as well as changes to the DNA structure of the sperm. Though the test subject group was limited to 24 participants, and additional research would be required to identify the specific risks of marijuana use to sperm, the study data did appear to correspond to results from previous studies.

    According to Live Science, the Duke University study – published in the journal Epigenics – is the first to illustrate the correlation between THC concentrations in urine and viable sperm count.

    Of the 24 participants – 12 of which were marijuana users and 12 of which were not – the sperm concentration in the latter group was twice as high as that of the former group. The study also noted epigenetic changes in sperm DNA among the former group – alterations to the “chemical tags,” as Live Science described them, that regulate gene expression. 

    The higher the concentration of THC in the test group’s urine, the more significant the changes to the sperm DNA, most notably in genes that help bodily organs reach their full size and for basic growth during development. A corresponding study on rats revealed a similar pattern in the same genes. However, such changes may not be permanent; sperm, damaged or not, are reabsorbed in the body if not ejaculated after 70 days.

    As lead author Susan Murphy – chief of the Division of Reproductive Sciences in the Department of Obstetrics and Gynecology at Duke – noted, “The sperm DNA . . . is not mutated in the traditional sense” by marijuana, and “epigenic alterations can affect gene regulation without changing the DNA sequence.” 

    Ultimately, the study could not determine whether the changes to sperm count and DNA determined by their study had an actual effect on fertilization or offspring, but Susan Murphy suggested that damaged sperm could have an adverse effect if it resulted in a viable embryo. In that case, individuals who are trying to conceive should consider abstaining from marijuana use 

    “In the absence of a larger, definitive study, the best advice would be to assume these changes are going to be there [in sperm],” she noted. “I would say, as a precaution, stop using cannabis for at least six months before trying to conceive.”

    View the original article at thefix.com