Tag: synthetic opioids

  • How Fentanyl Changed The Opioid Crisis

    How Fentanyl Changed The Opioid Crisis

    The prevalence and potency of illicit fentanyl has changed the course of the opioid crisis for the worse. 

    While prescription painkillers were previously attributed to the most deaths in the opioid epidemic, they no longer do. Instead, the leading cause of death in this context is now illegal fentanyl, according to a recent Bloomberg editorial.

    The National Center on Health Statistics states that in 2017, illegal fentanyl played a role in 60% of opioid deaths, in comparison to 11% of opioid deaths five years ago. 

    Fentanyl was created in 1960 and was used as a treatment for cancer pain. Illicit fentanyl has become common in the black market because it can be easily manufactured in a lab. Its potency also means it can be put into very small packages that are easy to conceal. 

    “Drug labs in China fulfill online orders from American users, or from traffickers in the U.S. and Mexico who add the fentanyl to heroin and other drugs to boost their effect, or press it into phony prescription-opioid pills,” the editorial reads. 

    Because of this, the editorial states, addressing the issue of illegal fentanyl needs to be focused first on China, which U.S. law enforcement officials claim is the source of nearly all illegal fentanyl. 

    The editorial states that the Obama administration had reached out to the Chinese government to ask for help in policing producers of fentanyl. But, with the Trump administration in place, that cooperation appears to have fallen by the wayside. 

    “What’s needed is a steady and purposeful diplomatic push, along with expert support for fortifying China’s capacity to inspect and regulate its thousands of drug labs,” the editorial board writes. 

    When fentanyl is exported from China, it mainly comes through the mail to both users and dealers. While Congress has allotted Customs and Border Protection more chemical-detection equipment, it is not possible to scan all packages entering the country. 

    “The task would be easier if Congress passed pending legislation to require the U.S. Postal Service to obtain basic identifying information from senders—including the name and address of sender and a description of package contents—as private parcel services do,” the editorial board writes.

    In addition to being sold on the dark web, fentanyl can also be found on regular websites, the board says. Scott Gottlieb, commissioner of the Food and Drug Administration (FDA), has spoken out about the need for internet companies to put more effort into taking down those listings. 

    While this all has to do with the supply, the aspect of demand must also be addressed, the board says. The more than 2 million Americans struggling with opioid or heroin use disorder need access to treatment, specifically medication-assisted treatment (MAT) and behavioral therapy.

    “Fentanyl and other opioids are killing more than 130 people a day. The crisis demands a thorough, well-coordinated national response. What the White House and Congress have come up with so far falls short,” the board concludes.

    View the original article at thefix.com

  • Couple Accused Of Running Mobile Home Drug Drive-Through

    Couple Accused Of Running Mobile Home Drug Drive-Through

    A string of overdose cases led authorities back to a mobile home with a makeshift drug-dealing drive through.

    Authorities busted a drug-dealing couple in Florida who were found running a drive-through service for illicit drugs out of the kitchen window of their mobile home. The drive-through experience was complete with signs directing traffic flow and open/closed signs.

    William Parrish Jr., 32, and McKenzee Dobbs, 20, reportedly put together the whole system, according to Ocala Police, to prevent their business from drawing unwanted attention from customers constantly entering and exiting their abode. But several overdoses in the area, presumably by their products, were what finally brought the long arm of the law to their door.

    “We were seeing some overdose incidents that were happening in this particular area, specifically at this particular location,” said Capt. Steven Cuppy of the Ocala Police. “There [were] some heroin sales that were going on there. Subsequently, through the investigation, we were able to determine that product was laced with fentanyl.”

    Parrish has been charged with driving under the influence, keeping a dwelling used to sell drugs, possession of drugs with intent to sell and resisting arrest without violence. Dobbs was slapped with keeping a dwelling used to sell drugs, possession of drugs with intent to sell, possession of fentanyl and possession of fentanyl with intent to sell.

    Parrish’s father, William Parrish Sr., claimed his son was trying to get his life back on track and was visiting a methadone clinic. “He’s been trying to get himself straightened out,” Parrish Sr. said.

    Parrish Sr. maintains that the reports of the overdoses are “a lie.”

    This isn’t the first time dealers have tried to use the convenience of a drive-through to do business. Last year, a pair of Burger King employees were caught using the fast food chain’s drive-through to deal cannabis.

    Customers in the know would speak to the drive-through in code, asking if “nasty boy” was working and, if so, if they could have their “fries extra crispy.”

    This was the cue for Garrett Norris, 20, and Meagan Dearborn, 19, to slip a little bit of marijuana in with the order and collect the payment at the second window. The pair were caught in a police sting, though Dearborn later claimed that she simply handed over the food and never knew what was stashed inside.

    View the original article at thefix.com

  • Stop Illegally Selling Opioids Online, FDA Warns

    Stop Illegally Selling Opioids Online, FDA Warns

    Over the summer, the FDA has issued similar warnings to 70 websites. 

    The Food and Drug Administration issued a warning this week to the operators of 21 websites that the administration says sell mislabeled and illegal opioids to Americans. 

    The websites, which are run by four companies, have been “illegally marketing potentially dangerous, unapproved, and misbranded versions of opioid medications, including tramadol,” according to a press release issued by the FDA on Tuesday (August 28). 

    “The illegal online sale of opioids represents a serious risk to Americans and is helping to fuel the opioid crisis. Cutting off this flow of illicit internet traffic in opioids is critical, and we’ll continue to pursue all means of enforcement to hinder online drug dealers and curb this dangerous practice,” FDA Commissioner Scott Gottlieb said in the news release.

    Over the summer, the FDA has issued similar warnings to 70 websites. 

    “The FDA remains resolute in our promise to continue cracking down on these networks to protect the public health,” Gottlieb said. “We have more operations underway, and additional actions planned. We are also working closely with legitimate Internet stakeholders, including leading social media sites, in these public health efforts.”

    People who buy their opioids online can often wind up with expired, counterfeit or contaminated pills, according to the FDA. Some of the pills are marketed under one name, but are really just pressed fentanyl, a dangerous synthetic opioid. On CNBC’s Squawk Box, Gottlieb said that online sales are making the ongoing opioid crisis worse.

    “As we see doctors prescribe fewer opioids, we’re fearful that more and more of the new addiction is going to shift to illicit sources, and a lot of those illicit sales are taking place online,” he said on Tuesday.

    The four companies that received warnings on Tuesday were CoinRX, MedInc.biz, PharmacyAffiliates.org and PharmaMedics. They have 10 days to respond to the FDA’s letter, outlining the specific actions that they will take to avoid selling illegal opioids to Americans. If the companies do not respond they may face legal action. 

    On Wednesday, Gottlieb said that the FDA will continue to aggressively pursue companies and practices that make opioids too easily available. 

    “The reason that we find ourselves with a crisis of such proportion is that as a medical profession, we’ve been one step behind its sinister advance,” he said in a press release.

    “Collectively, we didn’t take all the steps we could, when we could, to stop the advance of this crisis. We shunned hard decisions. As a profession, providers were too liberal in our use of these drugs well past the point where there were signs of trouble, and the beginning of a crisis of addiction. I’m committed to making sure that we don’t perpetuate these mistakes of the past. And so, when we see this crisis taking new twists and turns, we’ve acted swiftly.”

    View the original article at thefix.com

  • Fentanyl Present In 90% Of Drugs, Massachusetts Officials Warn

    Fentanyl Present In 90% Of Drugs, Massachusetts Officials Warn

    The synthetic opioid is found more in combination with cocaine and benzodiazepines than heroin.

    Officials in Massachusetts are warning the public that the presence of the deadly synthetic opioid, fentanyl, is increasingly common in all types of illicit drugs in the state—not just in heroin or other opioids—raising the overdose risk for users of cocaine and other illegal substances. 

    “If an individual is using illicit drugs in Massachusetts, there’s a very high likelihood that fentanyl, which is so deadly, could be present,” said Dr. Monica Bharel, commissioner of the state Department of Public Health, according to New England Public Radio. “Anybody using illicit drugs should understand the risks, carry naloxone, and access treatment.”

    The state’s quarterly report found that fentanyl is present in 90% of overdose deaths in Massachusetts. It is found more in combination with cocaine and benzodiazepines than with heroin. In 2014, fentanyl was found in less than 30% of overdose deaths in the Bay State. 

    Because fentanyl is becoming more prevalent in cocaine and benzodiazepines, officials are advising family members of people who use illicit drugs to carry naloxone, the opioid overdose reversal drug. People who do not use opioids regularly are more susceptible to fentanyl overdose because they have not built up an opioid tolerance. 

    Because of this, the state is urging healthcare providers to help all drug users get into treatment, not just those who report that their primary drug of choice is an opioid. 

    “When analyzing opioid overdose deaths, we have become aware that a significant portion of the deaths are associated with concurrent cocaine use,” the state wrote in a letter to providers. “We believe this information is useful for you in your clinical work. Additionally, patients should be aware that polysubstance use can NOT be a reason for refusal for admission in the treatment system.” 

    The report also showed that overdose deaths are declining in Massachusetts for the third straight quarter, even as such deaths continue to rise nationally. This could be due in part to the rising rates at which EMTs in the state are administering naloxone, as well as public health campaigns, Bharel said. 

    “In Massachusetts we have a multi-pronged approach,” she said. “This is about prevention, raising awareness in our communities, and raising awareness among our prescribers.” 

    However, not all demographics are seeing the improvement. Hispanics are disproportionately likely to die of an overdose in Massachusetts, and the overdose rates for black men continue to rise. 

    “While the results of our efforts are having an impact, we must double down on our efforts to implement treatment strategies that meet the needs of the highest risk individuals and communities,” Health and Human Services Secretary Marylou Sudders said in a statement.

    View the original article at thefix.com

  • Tunnel Beneath KFC Connects Drug Smugglers in Arizona, Mexico

    Tunnel Beneath KFC Connects Drug Smugglers in Arizona, Mexico

    The county sheriff’s department called the discovery a “heavy blow to that transnational criminal organization that built this tunnel.”

    A routine stop for an equipment violation led law enforcement in Arizona to an operation that numerous media outlets compared to the AMC series Breaking Bad, with a near-600-foot tunnel that connected a former fast food restaurant to a private home in Mexico for the purposes of trafficking narcotics.

    Police pulled over Jesus Ivan Lopez Garcia on August 13 after he was observed removing several containers from an abandoned Kentucky Fried Chicken (KFC) franchise located one mile from the U.S.-Mexico border; a search of the vehicle turned up more than 200 packages of various narcotics, including 6.8 pounds of fentanyl.

    This led to a search of the restaurant, where a tunnel traversed the border to a home in San Luis Rio Colorado, Mexico. The county sheriff’s department described the discovery as a “heavy blow to that transnational criminal organization that built this tunnel.”

    According to CNN, court documents showed that Lopez Garcia had purchased the former KFC location in San Luis, Arizona in April 2018. The structure was described as “vacant in recent years,” which raised the suspicion of police when Lopez Garcia was seen taking the containers, including a tool box from the former restaurant and loading them into a trailer attached to a pickup truck.

    Officers then pulled him over for what was described as an unspecified equipment violation, and during the traffic stop, a K-9 officer alerted authorities to suspected drugs in the two containers.

    A search of the containers yielded more than 261 pounds of methamphetamine, 14 pounds of cocaine, 30 pounds of white heroin, 13.7 pounds of brown heroin and 6.8 pounds of fentanyl.

    Homeland Security Investigations (HSI) Special Agent in Charge Scott Brown told a CNN affiliate station in Arizona that the fentanyl “translates to over three million dosage units.” Authorities gave the total price of the drugs at more than $1 million.

    After obtaining a warrant, HSI conducted a search of the KFC location on August 14 and found an eight-inch hole with a depth of 22 feet.

    This led to a walkway that was five feet tall and three feet wide that ran 590 feet across the border to San Luis Rio Colorado in Mexico. Mexican authorities reported that a search of a residential property on August 15 found an entrance to the tunnel under a bed. 

    “There was no mechanism to physically come up to the small opening” in the KFC location, said Brown in a press conference. “The narcotics we believe were raised up by a rope [and] then loaded into the tool box and taken out of the abandoned restaurant.”

    Yuma Sector Chief Patrol Agent Anthony Porvaznik said that the tunnel will be filled with cement to keep others from using it.

    View the original article at thefix.com

  • Woman Reportedly Caught With 1.5 Million Lethal Doses Of Fentanyl

    Woman Reportedly Caught With 1.5 Million Lethal Doses Of Fentanyl

    A woman traveling from Los Angeles to New York City was reportedly caught with five pounds of fentanyl in a suitcase.

    Authorities in Kansas City arrested a woman at a bus station who was traveling across the country, from Los Angeles to New York, carrying five pounds of fentanyl—reportedly enough of the drug to cause 1.5 million lethal overdoses.

    Kansas City Police noticed 33-year-old Evelyn C. Sanchez was “intently watching” detectives as they searched through the luggage on the bus.

    When asked, Sanchez told authorities she was heading to New York for “maybe a week,” but the story fell apart when officers reportedly noticed she had not packed a lot of clothing in her luggage.

    Following her questioning, K-9 units sniffed inside the bus and indicated a suitcase near Sanchez’s seat on the bus. When the other bus passengers did not claim the suitcase as theirs, police asked Sanchez and she admitted it was hers before allowing officers to search it.

    Authorities noted that she seemed “very nervous.”

    When asked, Sanchez told police she had “drugs,” according to court records. She did not seem to know what exactly she had, “but it’s a lot.”

    Officers checked inside and did indeed find a lot of drugs—over five pounds of fentanyl, “capable of killing thousands of people,” according to Kansas City Police Chief Rick Smith.

    Local authorities cooperated with the Drug Enforcement Administration (DEA) in the investigation. The DEA estimates the amount of fentanyl could kill several orders of magnitude more people than Smith’s estimates, claiming the operation took “1.5 million lethal doses from the streets.”

    There’s no telling where the fentanyl was ultimately heading yet, but it was almost guaranteed to help drive up the number of overdose deaths in the United States and further exacerbate the impact of the opioid crisis.

    Of 72,000 overdose deaths in 2017, 50,000 of those were opioid-related—30,000 of which were from fentanyl or related synthetic opioids.

    The drug is even getting to people who don’t want them—of 907 samples of drugs sold as heroin in Vancouver, Canada, 822 contained fentanyl.

    The U.S. Attorney’s office says Sanchez is in federal custody and awaiting a court date to be scheduled.

    View the original article at thefix.com

  • Trump To Jeff Sessions: Sue Drug Companies For Opioid Crisis Role

    Trump To Jeff Sessions: Sue Drug Companies For Opioid Crisis Role

    The Attorney General said he would take action on Trump’s requests. 

    President Donald Trump has instructed Attorney General Jeff Sessions to file a federal lawsuit against pharmaceutical companies in Mexico and China, claiming that they have played a role in the US opioid epidemic.

    Last week, according to the New York Post, the president threw blame at China and Mexico for their roles in the opioid epidemic, claiming the countries had manufactured some of the illegal opioids coming into the United States.

    “In China, you have some pretty big companies sending that garbage and killing our people. It’s almost like a form of warfare. I’d like you to do what you can legally,” Trump said to Sessions.

    Fox News reports that Trump’s remarks came during a Cabinet meeting on Thursday, Aug. 16. Fox notes it was somewhat unusual that Trump asked for a new “major” lawsuit to be filed, rather than asking Sessions to join existing lawsuits filed by various US states. 

    “I’d also like to ask you to bring a major lawsuit against the drug companies on opioids,” Trump stated at the meeting, according to Fox. “Some states have done it, but I’d like a lawsuit to be brought against these companies that are really sending opioids at a level that — it really shouldn’t be happening. … People go into a hospital with a broken arm, they come out, they’re a drug addict.”

    Sessions said he would take action on Trump’s requests. 

    “We absolutely will,” Sessions said at the meeting. “We are returning indictments now against distributors from China; we’ve identified certain companies that are moving drugs from China, fentanyl in particular. We have confronted China about it … Most of it is going to Mexico and then crossing the border, unlawfully, from Mexico.”

    As of now, more than 25 US states have filed more than 1,000 lawsuits against opioid distributors and manufacturers.

    Last week, New York filed a lawsuit against Purdue Pharma, stating the manufacturer of the painkiller OxyContin has mislead medical professionals and patients about the dangers of the medication. Massachusetts also filed a lawsuit against the company in June, accusing the company of a “web of illegal deceit.” 

    According to recent estimates, overall overdose deaths in the US in 2017 were about 72,000 — an increase of 6,000 from 2016’s estimates.

    However, preliminary 2018 data implies that the “numbers may be trending downward in the wake of the Trump administration’s efforts to curb the epidemic.”

    View the original article at thefix.com

  • Fentanyl Found In Startling Number Of Heroin Samples In Canada

    Fentanyl Found In Startling Number Of Heroin Samples In Canada

    “Something like 60% of the drugs that we check are not what people think they are,” said the author of a new drug-testing study.

    Drugs in Vancouver, Canada may be even more dangerous than normal, according to a new pilot project. 

    The project from the B.C. Centre on Substance Use (BCCSU) found that more than 80% of drugs sold as heroin in Vancouver do not actually contain heroin, but rather a dangerous synthetic opioid called fentanyl. 

    For the project, the BCCSU gave local users the opportunity to test their drugs for fentanyl as well as other substances. The study took place from November 2017 to April 2018 at two supervised-consumption sites in the Downtown Eastside part of Vancouver.

    In total, 1,714 samples were tested with fentanyl test strips and an infrared spectrometer. 

    The results, which the Globe and Mail reports will be published in September in the Drug and Alcohol Dependence journal, demonstrated that fentanyl was present in a great deal of local drugs, especially heroin. The project also found that types of drugs such as stimulants and hallucinogens are more likely to contain the substance they are sold as.

    The findings, according to co-author Mark Lysyshyn, give insight into how problematic the contamination of various drugs is locally. 

    “Something like 60% of the drugs that we check are not what people think they are,” Lysyshyn said on Tuesday, according to the Globe and Mail. “We’ve always had the idea that drugs could be something different, but right now [the contamination rate] is really high.”

    During the study, the Globe and Mail states, authors found that the majority of drug samples (58.7%) were expected to be opioids. They received 907 samples of what was thought to be heroin, but only 160 (17.6%) contained heroin. Of the total 907, 822 contained fentanyl. 

    Lysyshyn says the results aren’t necessarily indicative of the illegal drug market as a whole since the study was concentrated in downtown Vancouver. 

    He also added that the intention of the study was not to prove whether an illegal drug is safe, but instead to encourage those who use the drugs to seek out more information about what they are putting into their bodies. 

    “I don’t think the purpose of drug checking is to say, ‘These are safe; take them recklessly.’ That’s not what we’re trying to do,” he said, according to the Mail and Globe. “We’re saying, here’s a bit more information about these substances; they still could be risky. Because even if you find out there’s no fentanyl in your heroin, heroin causes overdoses, too. We don’t want people to forget all about the other harm-reduction advice that we’re giving; this is just additional information that we think could be helpful.”

    View the original article at thefix.com

  • 2017 Worst Year Yet for Drug Deaths

    2017 Worst Year Yet for Drug Deaths

    Last year has usurped the dubious title from 2016 with the most lives claimed by drug overdoses ever.

    According to a preliminary report by the Centers for Disease Control and Prevention (CDC), over 72,000 people in the United States died from a drug overdose in 2017. The number translates to nearly 200 people lost per day.

    This shatters the record previously held by the year 2016, which saw about 64,000 overdose deaths. In both 2016 and 2017, “at least” two-thirds of the deaths could be linked to the use of opioids.

    For comparison, the number of drug overdose deaths in 2017 exceeds the number killed by guns, car accidents, or HIV/AIDS within the span of a single year. The number is also larger than the casualties in both the Vietnam and Iraq conflicts combined.

    These figures are simply estimates, with more accurate figures due later. However, the CDC claims a trend is clear: the massive uptick is correlated to the rise of fentanyl.

    Fentanyl is an opiate stronger than heroin, sometimes used to lace other opioid products. Its potency makes it a dangerous high, especially when added to heroin, especially east of the Mississippi. But apparently, this “trend” is moving West.

    “Dr. [Chris] Jones said there is some early evidence that drug distributors are finding ways to mix fentanyl with black tar heroin, which could increase death rates in the West,” reported New York Times’ Margot Sanger-Katz. “If that becomes more widespread, the overdose rates in the West could explode as they have in parts of the East.”

    Fentanyl has been exacerbating the already burgeoning opioid crisis in the United States. Experts say the crisis is a fixable one, with one solid step in the right direction being making access to addiction treatment more available.

    In France, doctors were given the green light to prescribe buprenorphine in 1995, leading to a 79% decrease in opioid deaths in four years, Vox noted.

    Another recommended step would be to enact harm reduction policies, including needle exchanges and making naloxone, the overdose reversal drug, more available. Such measures have resulted in steep drop-offs of deaths in states that have put such plans in place.

    The Trump administration, however, has not made significant progress in these steps, according to Senator Elizabeth Warren.

    “Experts and observers have concluded that your efforts to address the opioid crisis are ‘pathetic,’ and ‘ambiguous promises’ that are ‘falling far short of what is needed’ are ‘not… addressing the epidemic with the urgency it demands,’” she wrote in a letter to President Trump. “I agree, and I urge you to move quickly to address these problems.”

    View the original article at thefix.com

  • Fentanyl, Other Synthetic Drugs Drive National Overdose Rates Up

    Fentanyl, Other Synthetic Drugs Drive National Overdose Rates Up

    Nearly 30,000 Americans died from overdoses stemming from fentanyl and other synthetic opioids in 2017.

    Driven in large part by widespread opioid use, the number of drug overdoses nationwide shot up nearly 10% last year, according to preliminary federal figures. 

    The U.S. clocked more than 72,000 drug fatalities in 2017, the Centers for Disease Control and Prevention (CDC) reported last week. That’s up by more than 6,000 from the 2016 figures, bringing the tally to nearly 200 deaths a day—more than the total number of gun, car crash or HIV deaths in any single year, ever. 

    But the new numbers—which represent a two-fold increase over 10 years ago—could actually be underestimating the true scope of the problem as full data from some states still isn’t in yet. 

    A big chunk of the increase—nearly 50,000 fatalities—comes from opioid deaths, a category that’s more than quadrupled since 2002. An increase in cocaine fatalities is also feeding into the higher figures. 

    Meanwhile heroin, painkiller, and methadone fatality figures have started to flatten out; it’s fentanyl deaths that are continuing to rise. Last year, close to 30,000 Americans died from overdoses stemming from fentanyl and other synthetic opioids.

    “Seventy-five percent of the deaths we get are fentanyl-related,”  Al Della Fave, a spokesman for the Ocean County, New Jersey prosecutor, told the Washington Post. “It’s the heroin laced with synthetic opioids that we’re getting creamed with.”

    The biggest increases are in some of the East Coast states already hardest hit by opioids, including Ohio, West Virginia and New Jersey. 

    In part, that’s due to the geography of drug-trafficking patterns. On the East Coast, heroin typically comes in a stronger powdered form—a form more easily mixed with deadly fentanyl. But in the western part of the country, cartels bring in black tar heroin from Mexico, which is both weaker and harder to mix with fentanyl. 

    “It is the 2.0 of drugs right now, the synthetics,” Tom Synan, the police chief in Newtown, Ohio, told the Post

    The current influx in opioid fatalities is commonly traced back to the 1990s, when drugmakers pushed addictive painkillers and doctors overprescribed them.

    Over a decade later, heroin took hold again when a cheap supply reshaped the market. But in recent years, it’s the introduction of fentanyl and other powerful synthetics that has driven the crisis to a deadlier point.

    And now that there’s finally been a downturn in some types of opioid fatalities, experts predict that any downward trend could be gradual given the nature of addiction and the stigma surrounding it.

    “Because it’s a drug epidemic as opposed to an infectious disease epidemic like Zika, the response is slower,” University of California San Francisco professor Dan Ciccarone told the New York Times. “Because of the forces of stigma, the population is reluctant to seek care. I wouldn’t expect a rapid downturn; I would expect a slow, smooth downturn.”

    View the original article at thefix.com