Category: Addiction News

  • Can The "Love Hormone" Help Treat Alcohol Use Disorder?

    Can The "Love Hormone" Help Treat Alcohol Use Disorder?

    Scientists examined whether oxytocin, also known as the love hormone, could be a viable treatment for alcohol use disorder.

    When administered nasally, a spray of oxytocin led alcohol-dependent rats to drink less, a new study has found

    Lead study author Brendan Tunstall, a post-doctoral fellow at the National Institute on Drug Abuse (NIDA), tells Inverse that his belief is that eventually, oxytocin could be a form of treatment for alcohol use disorder. 

    “Preliminary studies in humans have already indicated that oxytocin may have beneficial effects in reducing physical signs of alcohol withdrawal and decreasing alcohol craving,” he tells Inverse.

    “However, larger studies are needed to determine the potential therapeutic usefulness of intranasal oxytocin administration for alcohol use disorder.”

    Oxytocin, commonly referred to as the “love hormone,” is a neuropeptide, meaning it signals the brain during “tender situations.”

    To determine whether oxytocin works for treating alcohol use disorder, Tunstall and his team took a group of alcohol-dependent rats and a non-dependent control group and gave them both a dose nasally. 

    Afterwards, when they were exposed to alcoholic drinks, the alcohol-dependent rats did not choose to drink them. They did, however, still drink sugar water. The control group did not show any differences. Tunstall says this shows that the oxytocin affected the rats’ desire for alcohol specifically.  

    The reasoning behind this, Tunstall says, has to do with gamma amminobutyric acid (GABA) signaling in the brain. In the past, it has been proven that GABA signaling increases for those with short and long-term alcohol use. Tunstall and his team wanted to determine whether oxytocin would help GABA signal levels return to normal. 

    “Together, these results provide converging evidence that oxytocin specifically and selectively blocks the enhanced motivation for alcohol drinking that develops in alcohol dependence likely via a central mechanism that may result from altered oxytocin effects on CeA GABA transmission in alcohol dependence,” the study authors wrote. “Neuroadaptations in endogenous oxytocin signaling may provide a mechanism to further our understanding of alcohol use disorder.”

    In previous experiments with rats, Tunstall and his team determined that alcohol led to “hyperactive GABA signaling,” which was no surprise. But they also found that oxytocin seemed to lessen the effects of GABA signals when it came to the rats, which they think could be responsible for the changes they have observed in the alcohol-dependent rats.  

    Even though the results of this recent study indicate that oxytocin could be helpful in treating alcohol use disorder, Tunstall says the study only examines the neuropeptide’s effect on one neuron category in the brain. This could be problematic if alcohol use disorder is rooted in another area of the brain entirely, he says. 

    View the original article at thefix.com

  • Atlanta May Soon Ban Smoking In Public Places

    Atlanta May Soon Ban Smoking In Public Places

    Atlanta already passed a smoking ban for outdoor parks in 2012.

    Under a new bill, Atlanta, Georgia could soon join the growing number of cities that have banned smoking in public places. 

    According to the Atlanta Journal Constitution, the new legislation would prohibit smoking in various public spaces, including Hartsfield-Jackson International Airport (by getting rid of smoking lounges), restaurants and bars, hotels, motels, stores, offices, public transit, restrooms and parking structures.

    Smoking within five feet of the entrances of such places, windows and ventilation systems would also be prohibited, the AJC reports. 

    “If people wish to smoke in public, we simply ask that they step outside,” said city council member Matt Westmoreland. “Legislation like this saves lives. It creates a safer, healthier city.”

    In 2012, Atlanta passed a smoking ban for outdoor parks. Under the proposed legislation, the definition of smoking would be expanded to also include e-cigarettes or vaping. However, this excludes facilities like cigar bars and hookah lounges that meet certain sales thresholds. 

    Some restaurants in the area already ban smoking while others allow it, according to the AJC. This is because back in 2005, Georgia passed what it called a smoke-free law, which allowed restaurants and bars to allow smoking under certain circumstances. 

    Currently, according to Georgia Restaurant Association CEO Karen Bremer, it’s estimated that less than 10% of restaurants in the area allow smoking.

    Tommy Webb, owner of Northside Tavern, currently allows it but says he is open to the idea of becoming a non-smoking space.

    “People have been pushing me to go to non-smoking… It is a question that comes up often and I’m caught in the middle,” Webb told the AJC. “I’m rolling with the times.”  

    Officials at Hartsfield-Jackson International Airport—the country’s busiest airport—have been planning to convert existing smoking lounges into shops or restaurants. According to the AJC, the airport is one of only five in the U.S. that still allows smoking.

    Delta Air Lines, based in Atlanta, expressed in a statement that the airline supports the idea of a smoke-free airport. “Employees and customers who work and travel through ATL every day deserve a safe and healthy environment,” the statement read. 

    Moving forward, Westmoreland says he plans to hold a work session in May during which the ordinance would be discussed.

    If approved by committees and the full council, the ordinance may be in effect by September 1 of this year. 

    View the original article at thefix.com

  • John Oliver Takes On Sackler Family, Opioid Epidemic

    John Oliver Takes On Sackler Family, Opioid Epidemic

    “Last Week Tonight” tackled the opioid epidemic again—this time putting the spotlight on the Sackler family members who have reportedly played a role in it.

    John Oliver spotlighted the opioid epidemic for the second time on HBO’s Last Week Tonight. This time, the late-night host recruited the help of actors Michael Keaton, Bryan Cranston and more, to bring to life the 2015 deposition of former Purdue Pharma president Richard Sackler about the company’s marketing of OxyContin

    Oliver addressed the Sackler family members’ alleged role in the opioid epidemic, drawing from pages of legal documents that are being made public as more and more municipalities sue the giant drug manufacturer, most famous for marketing OxyContin

    He pointed out that the billionaire Sackler family, while donating to arts and research institutions around the world, has made an effort to stay out of the public eye. In fact, Oliver said, there are very few photos, let alone video footage, of Richard Sackler available in the public domain. 

    So, Oliver brought in actors to read the transcript of Sackler’s deposition in a 2015 case brought by the state of Kentucky. Purdue settled with the state on the condition that millions of pages of documents brought as evidence be destroyed, but the deposition was leaked and Last Week Tonight made the entire 140-page document available online

    The show also put together a website, The Sackler Gallery, to showcase the family’s role in the opioid crisis. On the website, actors Bryan Cranston, Michael Keaton, Richard Kind and Michael K. Williams give life to Richard Sackler’s testimony. 

    “The launch of OxyContin tablets will be followed by a blizzard of prescriptions that will bury the competition,” Williams says in one clip, repeating Sackler’s infamous proclamation. “The prescription blizzard will be so deep, dense and white.” The Sacklers have said that this comment was taken out of context.

    In another clip, the actors repeat Sackler’s proclamation that people who abused opioids were to blame for the epidemic. He referred to them as “criminals,” trying to shift the blame away from himself. 

    Oliver rightly noted that while Sackler seemed to take issue with these people’s excessive drug use, his company did nothing to curb suspicious drug sales that were earning the company billions. 

    “He is furious at the people who are part of the problem, but the people he’s angry at helped make him incredibly rich,” Oliver said. “You don’t see Adam Levine making a song condemning horny middle aged women because that would make him hypocritical.”

    View the original article at thefix.com

  • NYC Bill Aims To End Marijuana Testing Of Job Applicants

    NYC Bill Aims To End Marijuana Testing Of Job Applicants

    The bill is one of several efforts being made to reform marijuana policy while progress has stalled on legalizing it statewide.

    New York City may become the first jurisdiction in the country to pass a law that would explicitly bar employers from screening job applicants for marijuana use.

    The city council “overwhelmingly” passed a bill (with a 40-4 vote) that would prevent most employers from this practice, the New York Times reports.

    “If we want to be a progressive city, we have to really put these things into action,” said the city’s public advocate Jumaane D. Williams, who authored the bill.

    Mayor Bill de Blasio has signaled his support of the legislation, which according to the NYT would be the first in the U.S. to prohibit employers from marijuana testing job applicants.

    If enacted, the law will affect both public and private employers in New York City, including companies that have headquarters elsewhere, Williams said.

    The bill would not excuse every worker from being tested, however. A handful of occupations—including construction, law enforcement, child care, medical care, truck driving and aviation—would be exempt from the rule. Employers may also test workers if they appear to be under the influence of marijuana at work. Federal or state employees and government contractors are also exempt as they do not fall under the city’s jurisdiction.

    The mayor is expected to sign the bill into law. It is one of several efforts being made to reform marijuana policy while progress has stalled on legalizing it statewide.

    Another bill passed by the city council would stop the city from requiring marijuana testing for people on probation, according to the NYT.

    NY lawmakers have made little progress on marijuana legalization, but Governor Andrew Cuomo’s office told CBS News that he was “still negotiating to legalize marijuana by the end of the legislative session in June.” Issues like equity programs—to ensure that people of color are guaranteed a stake in the growing industry to make up for years of being disproportionately affected by anti-marijuana laws—have gotten in the way of reaching a deal thus far.

    “I’m proud that the city has taken action where the federal and the state government have stalled,” said Williams.

    In 1986, former President Ronald Reagan issued an executive order calling for “drug-free workplaces,” mandating drug testing at federal agencies. According to a survey by the Society for Human Resource Management, in 2011 more than half of U.S. employers conducted drug screenings on job applicants.

    However, some disagree that drug testing is a reliable method of predicting job performance.

    View the original article at thefix.com

  • Legal Battle Over Safe Injection Site Could Be Game Changer For US

    Legal Battle Over Safe Injection Site Could Be Game Changer For US

    Safehouse is engaged in a historic legal battle with the government over their attempt at opening the country’s first safe injection site.

    The outcome of a legal battle over whether to open the nation’s first supervised injection facility (SIF) rages on in Philadelphia. The result could influence other efforts to do the same elsewhere in the U.S.

    In February, Pennsylvania prosecutors and the federal Department of Justice filed a civil lawsuit attempting to stop a local non-profit organization, Safehouse, from opening SIF locations in Philadelphia.

    They cite the “crack house statute” under the Controlled Substances Act, which made it a crime to “knowingly open, lease, rent, use, or maintain any place, whether permanently or temporarily… for the purpose of unlawfully manufacturing, storing, distributing, or using a controlled substance.”

    In response, Safehouse is countersuing the government in federal court. They argue that the “crack house statute” does not apply to SIFs. “Safehouse is nothing like a ‘crack house’ or drug-fueled ‘rave.’ Nor is Safehouse established ‘for the purpose’ of unlawful drug use,” stated Ilana Eisenstein, a lawyer for Safehouse.

    They argue that SIFs are less about drugs and more about providing a medical service. By giving people a safe place to use under medical supervision rather than alone on the street, SIFs save lives. Another important feature of SIFs, proponents say, is that they offer access to treatment and support. 

    “If you find a place that accepts the fact that you’re going to be consuming drugs and still offers you services in a non-judgmental way, you’re going to start to trust them,” says Ronda Goldfein, vice president and co-founder of Safehouse. “And once there’s a trust relationship, you’re more inclined to accept the range of treatment they’re offering, which includes recovery.”

    Safehouse also cites the Religious Freedom Restoration Act of 1993 in its countersuit. “[This] service is an exercise of the religious beliefs of its Board of Directors, who hold as core tenets preserving life, providing shelter to neighbors, and ministering to those most in need of physical and spiritual care,” stated Safehouse lawyer Eisenstein.

    Seattle, New York, Denver, Maryland, Maine and more are also considering opening supervised injection facilities, as opioid abuse and overdose have become increasingly problematic throughout the country.

    William McSwain, the U.S. Attorney for the Eastern District of Pennsylvania who is suing Safehouse, says the outcome of the legal battle could have a ripple effect across the U.S.

    “This is something that I think people will be looking at as, in a sense, a test case that will have implications in other districts,” he said.

    View the original article at thefix.com

  • Artie Lange "Doing Well" In Recovery, Working On Court-Ordered Community Service

    Artie Lange "Doing Well" In Recovery, Working On Court-Ordered Community Service

    One of Lange’s close friends released a video of the comedian participating in his court-ordered community service.

    Artie Lange appears to be making positive progress in early recovery after being taken into custody in January, when he tested positive for both morphine and cocaine

    Lange, a 51-year-old actor and comedian known for his roles on the Howard Stern Show and Mad TV, has long struggled with substance use disorder. At the time of his arrest, he was ordered to take part in mandatory drug rehab, Consequence of Sound reports.  

    A few days ago, Russ Meneve, a friend of Lange’s, tweeted a video of the actor cleaning up garbage as part of his community service and treatment. 

    “Just spoke to one of my greatest friends, Artie Lange, who’s doin’ great in recovery and asked me to share this vid of him “on the job” !!” his tweet read. “He looks great and will be back soon. Stay tuned and keep rootin’ for a truly great human being…we love ya, Art.”

    In the shared video, Lange says to Meneve, “You’re going to keep this quiet, right, I’m sure.” 

    Meneve responds, “Absolutely. No one will ever know, ” to which Lange replies “I love you!” and “Take care.”

    The video was also shared on Lange’s Twitter account, which read “We heard from Artie this morning, HA!” then added this snipped from Lange: “It’s true i’m working to satisfy my drug court program. I work with great people. Nothing wrong with a little hard work. Love you all and can’t wait to be back on stage.”

    According to Page Six, Lange’s rep has verified that “this is work Artie is doing as part of his [New Jersey] drug court case. He is working with a refuse company daily as he continues treatment.”

    This was not the actor’s first run-in with drug-related trouble. Last June, Lange was given four years of probation, 50 hours of community service and was instructed to attend outpatient treatment. Despite the charges, he was not given any jail time.

    “The judge and Prosecutor were unbelievably compassionate,” Lange tweeted at the time. “I’m not high. So I see it clearly now. They wanna save my life. 10 days ago when I left rehab I had to touch the flame. I used Cocaine.”

    Lange has been fairly open about his struggles. In December last year, he posted a photo of his nose on Instagram and called it “hideously deformed.” The reason for that, Fox News reported at the time, was accidentally snorting broken glass that had been mixed with Oxycontin

    At the time, some of Lange’s friends reached out on Twitter

    “Artie, this is my 1000th request over decades to beg you to surrender to your addictions,” Richard Lewis tweeted. “We had the most laughs sober. I love you. You’re beloved and a magnificent comedian cursed with self loathing and fear. Give it up and live.”

    View the original article at thefix.com

  • "Miles Davis: Birth of the Cool" Connects Jim Crow Oppression to Davis' Heroin Addiction

    "Miles Davis: Birth of the Cool" Connects Jim Crow Oppression to Davis' Heroin Addiction

    Miles Davis’ heroin addiction and alcoholism are all well known and well documented. However, Nelson frames this period as resulting from Davis’ return to a reality in which he was not wanted but his music was.

    The documentary Miles Davis: Birth of the Cool opened up the world of one of the most innovative musicians in American history. In the film, Director Stanley Nelson laid bare all the details of the music man’s life, including the darkness and despair of Davis’s struggle with alcoholism and heroin addiction. It is during this piece of the film, which should have been the low and slow point, that the pieces Nelson offered began to connect. Davis’s heroin addiction was a direct result of the treatment he received as a black man living under Jim Crow laws in 1949.

    In the documentary, Nelson offers audiences the French tour where Miles Davis discovered love and existence without the restriction and oppression of Jim Crow America post-WWII. Davis went to France in 1949, touring with the Tadd Dameron group for quite some time. By all accounts—even those outside of Nelson’s documentary—the man became enamored with the country that embraced him for his talent without placing restrictions on him due to his skin color. Here he experienced life without the heavy hand of racism weighing him down.

    The freedom of living abroad was buoyed by a romance with a French singer named Juliette Gréco. The couple, despite their racial differences, was able to maintain a public relationship just like other couples in France and much of Europe. The oppressive, dangerously restrictive Jim Crow laws in the U.S. would have made their relationship illegal. American laws and policies in 1949 were enacted to maintain the belief that black people were inferior to their white countrymen.

    In Birth of the Cool, the narrator discusses how Davis became “disillusioned” by American racism after spending quite some time away in France. The weight of Jim Crow was enough to send the musician into a depression that he could not recover from. This was compounded by the lull in his musical career because of the waning popularity of bebop and the lack of a fresh new sound from Davis. He was also mulling the loss of the relationship that he would remember well into his later years. Davis told an interviewer that he never married Gréco because he loved her and wanted her to be happy. Their marriage could not exist in the U.S.

    The next part of the documentary was a slow plunge into the darkest parts of the musician’s life. Davis’s heroin addiction and alcohol abuse are all well known and well documented. However, Nelson frames this period as resulting from Davis’s return to a reality in which he was not wanted but his music was. Although Nelson never explicitly says so, the racism Davis experienced led to his depression, which sent him into the heroin addiction and alcoholism rabbit hole. Even in the documentary, Davis describes his depression as something that sprouted the moment he returned to the racist United States and followed him through the period of his life where he struggled with addiction.

    Studies like “Exploring the Link between Racial Discrimination and Substance Use: What Mediates? What Buffers?” from the Journal of Personality and Social Psychology show that not only is there a relationship between racism and mental health issues as a whole, but the link also exists specifically between racism and addiction. The authors write, “Psychologists have known for some time about the pernicious effects that perceived racial discrimination can have on mental health.” The study goes on to dig into the research gathered from this link. They found that “[n]umerous correlational studies have documented relations between self-reports of discriminatory experiences and reports of distress, including anxiety and depression, as well as anger.” All of these elements were likely in place as Davis returned to the U.S. The weight of segregation, sundown laws, lynchings, and other trappings of Jim Crow laws was more than enough to anger and depress any black person at the time.

    Substance use promises an escape from pain and Davis needed a way to cope with all these feelings. According to the aforementioned study, “[T]he increased substance use we found was evidence of a coping style that includes use as a means of handling the stress of discrimination.” Davis probably became more angered and frustrated with the racist behavior (especially after returning home to the predominantly white St. Louis suburb his parents lived in). The documentary also described how his musical popularity waned and his personal life was disrupted from the breakup with Gréco. At the time, the musician’s life had all the elements in place to breed the raging heroin addiction that followed.

    Fortunately, Davis recovered from his addiction to opioids and alcohol, but it was a lifelong struggle. Nelson depicts as much in the documentary. In fact, racism and substance abuse become a very strong subplot to the documentary that works to educate viewers as much as entertain them. Between the scenes depicting the origins of the famous everchanging Miles Davis sound, Nelson buried important nuggets that should force us to redefine how we view and treat racism and addiction.

    Birth of the Cool essentially describes the environment from which Miles Davis’s addiction was created. There are other factors that also affected his addiction, but racism and depression were the primary and most powerful drivers that pushed him toward problematic substance use. Nelson thus lends one more voice to the chorus of stories that illustrate how racism and the oppression of white supremacy is an impetus to substance misuse and addiction. Acknowledging this can help with not only treating addiction in the black community, but also with understanding why racism should be considered a public health concern worthy of more serious attention.

    More info on Miles Davis: Birth of the Cool here.

    View the original article at thefix.com

  • Ketamine's Effect On Depression Examined

    Ketamine's Effect On Depression Examined

    A new study offers a better understanding of the way ketamine helps lift depression symptoms.

    Last month, the FDA approved a ketamine-based depression treatment for certain patients.

    The drug, esketamine, is said to relieve depression symptoms “in hours instead of weeks,” marketed for people who haven’t found success in other antidepressants.

    While it is yet unknown how exactly ketamine helps lift depression symptoms, a new study gives us a better understanding of how it works.

    The research confirms that ketamine triggers synapse growth, effectively rewiring the brain, Scientific American reports. They were able to “visualize and manipulate” the brains of stressed mice—demonstrating how ketamine first changes brain circuit function that improved behavior in “depressed mice” in up to 3 hours. Later, the drug stimulated regrowth of synapses in the brain.

    “It’s a remarkable engineering feat, where they were able to visualize changes in neural circuits over time, corresponding with behavioral effects of ketamine,” said Carlos Zarate of the National Institute of Mental Health, who was not involved in the study. “This work will likely set a path for what treatments should be doing before we move them into the clinic.”

    “Our findings open up new avenues for research, suggesting that interventions aimed at enhancing the survival of these new synapses might be useful for extending ketamine’s antidepressant effects,” said study lead Conor Liston of Weill Cornell Medicine.

    In March, the Food and Drug Administration (FDA) approved esketamine (also known as Spravato) for people who did not respond to at least two other antidepressant treatments. The drug can only be administered under supervision by one’s doctor, and is said to relieve depression in just hours.

    “There has been a long-standing need for additional effective treatments for treatment-resistant depression, a serious and life-threatening condition,” said Dr. Tiffany Farchione of the FDA.

    Ketamine differs from traditional antidepressants by acting on glutamate, a chemical messenger in the brain, rather than the “monoamine” neurotransmitters (serotonin, norepinephrine, dopamine) that traditional antidepressants act on. Glutamate plays an important role in the changes that synapses undergo in response to experiences that underlie learning and memory, Scientific American explains.

    A 23-year-old man suffering from depression, anxiety and other mental disorders shared his experience with ketamine infusion therapy with The Fix. “It helped with every aspect: anxiety, depression, psychosis. I know that’s not what it’s for, but in my case it changed everything,” he said.

    However, medical providers caution that while ketamine shows a lot of promise, there’s still more research to be done on its long-term effects on mental health patients.

    View the original article at thefix.com

  • Joe Biden: '80s Anti-Drug Bills Were "Big Mistake"

    Joe Biden: '80s Anti-Drug Bills Were "Big Mistake"

    “The big mistake was us buying into the idea that crack cocaine was different from the powder cocaine, and having penalties… it should be eliminated,” said Biden.

    Former Vice President Joe Biden again voiced regret for his support of a 1980s-era anti-drug bill that imposed tougher penalties and prison sentences for drug offenses that, in turn, bolstered disproportionate rates of incarceration in black and Latino communities.

    Speaking at a panel on opioid addiction at the University of Pennsylvania on April 11, Biden said that it was a “big mistake” to support the Anti-Drug Abuse Act of 1988 which levied more severe sentencing for possession of crack cocaine, a substance more predominantly found in communities of color, than for possession of powder cocaine

    But Biden, who is weighing his options in regard to a 2020 presidential bid, also noted that the crime bills added drug courts, which he viewed as a positive alternative to incarceration.

    Biden, who serves as Presidential Professor of Practice at UPenn, was joined on the panel by former Florida Governor Jeb Bush and Philadelphia Mayor Jim Kenney. The panel addressed the national opioid epidemic and efforts to address legal and cultural issues regarding addiction and drug use.

    Biden weighed in on several topics in the discussion, including the overwhelming amount of advertising dollars spent by pharmaceutical companies to promote opioid medications, which he described as “criminal.”

    Biden also said that closer negotiations with countries like China and Mexico, which are regarded as major sources of illicit narcotics, and increases in port security and technology to aid in detection—which he acknowledged was a missed opportunity by the Obama administration—would both help curb the flow of drugs into the United States. Biden specifically targeted President Donald Trump’s efforts to build a security barrier between the U.S. and Mexico while discussing this topic.

    “Instead of building more barriers, we could take one-tenth the amount of money talked about building the wall and significantly increase the technological capacity at ports of entry,” he noted.

    And in regard to the aforementioned crime bills, which Biden sponsored—and in the case of the 1986 bill, co-authored—he reiterated statements made at other public events in which he admitted that there had been missteps in his efforts towards criminal sentencing.

    “The big mistake was us buying into the idea that crack cocaine was different from the powder cocaine, and having penalties… it should be eliminated,” said Biden.

    And while acknowledging that he “[gets] beat up on the crime bill,” Biden also said that in his mind, there was also a positive outcome to his efforts.

    “The crime bill put in drug courts,” he said. “I think we have to do a whole lot more of that diversion to have an impact.”

    View the original article at thefix.com

  • Kratom-Related Deaths Analyzed By The CDC

    Kratom-Related Deaths Analyzed By The CDC

    The herbal supplement has been targeted as a “drug of concern” by the FDA and DEA.

    The number of deaths associated with kratom appears to be rising.

    A new report by the CDC analyzed data from 27 states on 27,338 overdose deaths between July 2016 and December 2017. A small number was attributed to kratom.

    “Kratom was determined to be a cause of death (i.e., kratom-involved) by a medical examiner or coroner for 91 of the 152 kratom-positive decedents, including seven for whom kratom was the only substance to test positive on postmortem toxicology, although the presence of additional substances cannot be ruled out,” the report read.

    The herbal supplement credited with helping recovery from substance use disorder has been targeted as a “drug of concern” by the Food and Drug Administration (FDA) and Drug Enforcement Administration (DEA).

    Some people in recovery say the plant, native to Southeast Asia, was vital to their recovery from drugs and alcohol, chronic pain, post-traumatic stress disorder (PTSD) and more. But with every success story, there is a person struggling to quit kratom as well.

    A majority of the kratom-involved deaths involved people with a history of substance use disorder. A significant majority of the kratom-positive decedents were Caucasian.

    The data also showed that “multiple substances [were] detected for almost all decedents.” The most common were fentanyl and fentanyl analogs, then heroin, benzodiazepines and prescription opioids.

    The FDA has railed hard against kratom, stating last year that “compounds in kratom make it so it isn’t just a plant—it’s an opioid.”

    The February 2018 statement cited 44 deaths associated with kratom use. Prior to that, in a November 2017 advisory, the FDA reported 36 deaths related to kratom.

    The FDA said it is “especially concerned” about people who use kratom to treat opioid withdrawal, and though it states that it is open to reviewing evidence that kratom does have healing properties, it so far has not come across any “that would meet the agency’s standard for approval,” and warns against using kratom to treat medical conditions or as an alternative to prescription opioids.

    “While kratom may have useful effects, right now, it’s wholly unregulated,” Henry Spiller, director of the Central Ohio Poison Center, told ABC News.

    Only a few U.S. states have outright banned the plant. Some states are considering legislation to regulate the plant, rather than prohibiting it.

    View the original article at thefix.com